🦋Science: On Data Visualization (Quotes)

"When visualization tools act as a catalyst to early visual thinking about a relatively unexplored problem, neither the semantics nor the pragmatics of map signs is a dominant factor. On the other hand, syntactics (or how the sign-vehicles, through variation in the visual variables used to construct them, relate logically to one another) are of critical importance." (Alan M MacEachren, "How Maps Work: Representation, Visualization, and Design", 1995)

"The nature of maps and of their use in science and society is in the midst of remarkable change - change that is stimulated by a combination of new scientific and societal needs for geo-referenced information and rapidly evolving technologies that can provide that information in innovative ways. A key issue at the heart of this change is the concept of ‘visualization’." (Alan M MacEachren, "Exploratory cartographic visualization: advancing the agenda", 1997)

"Visualizations can be used to explore data, to confirm a hypothesis, or to manipulate a viewer. [...] In exploratory visualization the user does not necessarily know what he is looking for. This creates a dynamic scenario in which interaction is critical. [...] In a confirmatory visualization, the user has a hypothesis that needs to be tested. This scenario is more stable and predictable. System parameters are often predetermined." (Usama Fayyad et al, "Information Visualization in Data Mining and Knowledge Discovery", 2002) 

"Dashboards and visualization are cognitive tools that improve your 'span of control' over a lot of business data. These tools help people visually identify trends, patterns and anomalies, reason about what they see and help guide them toward effective decisions. As such, these tools need to leverage people's visual capabilities. With the prevalence of scorecards, dashboards and other visualization tools now widely available for business users to review their data, the issue of visual information design is more important than ever." (Richard Brath & Michael Peters, "Dashboard Design: Why Design is Important," DM Direct, 2004)

"Data visualization [...] expresses the idea that it involves more than just representing data in a graphical form (instead of using a table). The information behind the data should also be revealed in a good display; the graphic should aid readers or viewers in seeing the structure in the data. The term data visualization is related to the new field of information visualization. This includes visualization of all kinds of information, not just of data, and is closely associated with research by computer scientists." (Antony Unwin et al, "Introduction" [in "Handbook of Data Visualization"], 2008) 

"The main goal of data visualization is its ability to visualize data, communicating information clearly and effectively. It doesn’t mean that data visualization needs to look boring to be functional or extremely sophisticated to look beautiful. To convey ideas effectively, both aesthetic form and functionality need to go hand in hand, providing insights into a rather sparse and complex dataset by communicating its key aspects in a more intuitive way. Yet designers often tend to discard the balance between design and function, creating gorgeous data visualizations which fail to serve its main purpose - communicate information." (Vitaly Friedman, "Data Visualization and Infographics", Smashing Magazine, 2008)

"With the ever increasing amount of empirical information that scientists from all disciplines are dealing with, there exists a great need for robust, scalable and easy to use clustering techniques for data abstraction, dimensionality reduction or visualization to cope with and manage this avalanche of data."  (Jörg Reichardt, "Structure in Complex Networks", 2009)

"So what is the difference between a chart or graph and a visualization? […] a chart or graph is a clean and simple atomic piece; bar charts contain a short story about the data being presented. A visualization, on the other hand, seems to contain much more ʻchart junkʼ, with many sometimes complex graphics or several layers of charts and graphs. A visualization seems to be the super-set for all sorts of data-driven design." (Brian Suda, "A Practical Guide to Designing with Data", 2010)

"All graphics present data and allow a certain degree of exploration of those same data. Some graphics are almost all presentation, so they allow just a limited amount of exploration; hence we can say they are more infographics than visualization, whereas others are mostly about letting readers play with what is being shown, tilting more to the visualization side of our linear scale. But every infographic and every visualization has a presentation and an exploration component: they present, but they also facilitate the analysis of what they show, to different degrees." (Alberto Cairo, "The Functional Art", 2011)

"The first and main goal of any graphic and visualization is to be a tool for your eyes and brain to perceive what lies beyond their natural reach." (Alberto Cairo, "The Functional Art", 2011)

"Thinking of graphics as art leads many to put bells and whistles over substance and to confound infographics with mere illustrations." (Alberto Cairo, "The Functional Art", 2011)

"Good infographic design is about storytelling by combining data visualization design and graphic design." (Randy Krum, "Good Infographics: Effective Communication with Data Visualization and Design", 2013)

"Good visualization is a winding process that requires statistics and design knowledge. Without the former, the visualization becomes an exercise only in illustration and aesthetics, and without the latter, one of only analyses. On their own, these are fine skills, but they make for incomplete data graphics. Having skills in both provides you with the luxury - which is growing into a necessity - to jump back and forth between data exploration and storytelling." (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"The biggest thing to know is that data visualization is hard. Really difficult to pull off well. It requires harmonization of several skills sets and ways of thinking: conceptual, analytic, statistical, graphic design, programmatic, interface-design, story-telling, journalism - plus a bit of 'gut feel'. The end result is often simple and beautiful, but the process itself is usually challenging and messy." (David McCandless, 2013)

"Visualization can be appreciated purely from an aesthetic point of view, but it’s most interesting when it’s about data that’s worth looking at. That’s why you start with data, explore it, and then show results rather than start with a visual and try to squeeze a dataset into it. It’s like trying to use a hammer to bang in a bunch of screws. […] Aesthetics isn’t just a shiny veneer that you slap on at the last minute. It represents the thought you put into a visualization, which is tightly coupled with clarity and affects interpretation." (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"Visualization is what happens when you make the jump from raw data to bar graphs, line charts, and dot plots. […] In its most basic form, visualization is simply mapping data to geometry and color. It works because your brain is wired to find patterns, and you can switch back and forth between the visual and the numbers it represents. This is the important bit. You must make sure that the essence of the data isn’t lost in that back and forth between visual and the value it represents because if you can’t map back to the data, the visualization is just a bunch of shapes." (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"What is good visualization? It is a representation of data that helps you see what you otherwise would have been blind to if you looked only at the naked source. It enables you to see trends, patterns, and outliers that tell you about yourself and what surrounds you. The best visualization evokes that moment of bliss when seeing something for the first time, knowing that what you see has been right in front of you, just slightly hidden. Sometimes it is a simple bar graph, and other times the visualization is complex because the data requires it." (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"Just because data is visualized doesn’t necessarily mean that it is accurate, complete, or indicative of the right course of action. Exhibiting a healthy skepticism is almost always a good thing." (Phil Simon, "The Visual Organization: Data Visualization, Big Data, and the Quest for Better Decisions", 2014)

"To be sure, data doesn’t always need to be visualized, and many data visualizations just plain suck. Look around you. It’s not hard to find truly awful representations of information. Some work in concept but fail because they are too busy; they confuse people more than they convey information [...]. Visualization for the sake of visualization is unlikely to produce desired results - and this goes double in an era of Big Data. Bad is still bad, even and especially at a larger scale." (Phil Simon, "The Visual Organization: Data Visualization, Big Data, and the Quest for Better Decisions", 2014)

"We are all becoming more comfortable with data. Data visualization is no longer just something we have to do at work. Increasingly, we want to do it as consumers and as citizens. Put simply, visualizing helps us understand what’s going on in our lives - and how to solve problems." (Phil Simon, "The Visual Organization: Data Visualization, Big Data, and the Quest for Better Decisions", 2014)

"Apart from the technical challenge of working with the data itself, visualization in big data is different because showing the individual observations is just not an option. But visualization is essential here: for analysis to work well, we have to be assured that patterns and errors in the data have been spotted and understood. That is only possible by visualization with big data, because nobody can look over the data in a table or spreadsheet." (Robert Grant, "Data Visualization: Charts, Maps and Interactive Graphics", 2019)

"As a first principle, any visualization should convey its information quickly and easily, and with minimal scope for misunderstanding. Unnecessary visual clutter makes more work for the reader’s brain to do, slows down the understanding (at which point they may give up) and may even allow some incorrect interpretations to creep in." (Robert Grant, "Data Visualization: Charts, Maps and Interactive Graphics", 2019)

"One very common problem in data visualization is that encoding numerical variables to area is incredibly popular, but readers can’t translate it back very well." (Robert Grant, "Data Visualization: Charts, Maps and Interactive Graphics", 2019)

"There is often no one 'best' visualization, because it depends on context, what your audience already knows, how numerate or scientifically trained they are, what formats and conventions are regarded as standard in the particular field you’re working in, the medium you can use, and so on. It’s also partly scientific and partly artistic, so you get to express your own design style in it, which is what makes it so fascinating." (Robert Grant, "Data Visualization: Charts, Maps and Interactive Graphics", 2019)

"The best approach is to build visualizations in the most digestible form, fitted to how that executive thinks. You will have to interact with executives, show them different visualizations, and see how they react in order to learn which forms work best for them. Be ready to fail often and learn fast, particularly with visualizations." (John Lucker)

"Visualisation is fundamentally limited by the number of pixels you can pump to a screen. If you have big data, you have way more data than pixels, so you have to summarise your data. Statistics gives you lots of really good tools for this." (Hadley Wickham)

"We often think of visualization as a design and programming task, but the process starts further back with the data. You have to understand the data - its trends and patterns, along with its flaws and imperfections - and the rest follows." (Nathan Yau)

🦋Science: On Data Collection (Quotes)

 "There are two aspects of statistics that are continually mixed, the method and the science. Statistics are used as a method, whenever we measure something, for example, the size of a district, the number of inhabitants of a country, the quantity or price of certain commodities, etc. […] There is, moreover, a science of statistics. It consists of knowing how to gather numbers, combine them and calculate them, in the best way to lead to certain results. But this is, strictly speaking, a branch of mathematics." (Alphonse P de Candolle, "Considerations on Crime Statistics", 1833)

"Just as data gathered by an incompetent observer are worthless - or by a biased observer, unless the bias can be measured and eliminated from the result - so also conclusions obtained from even the best data by one unacquainted with the principles of statistics must be of doubtful value." (William F White, "A Scrap-Book of Elementary Mathematics: Notes, Recreations, Essays", 1908)

"[...] scientists are not a select few intelligent enough to think in terms of 'broad sweeping theoretical laws and principles'. Instead, scientists are people specifically trained to build models that incorporate theoretical assumptions and empirical evidence. Working with models is essential to the performance of their daily work; it allows them to construct arguments and to collect data." (Peter Imhof, Science Vol. 287, 1935–1936)

"Statistics is a scientific discipline concerned with collection, analysis, and interpretation of data obtained from observation or experiment. The subject has a coherent structure based on the theory of Probability and includes many different procedures which contribute to research and development throughout the whole of Science and Technology." (Egon Pearson, 1936)

"Scientific data are not taken for museum purposes; they are taken as a basis for doing something. If nothing is to be done with the data, then there is no use in collecting any. The ultimate purpose of taking data is to provide a basis for action or a recommendation for action. The step intermediate between the collection of data and the action is prediction." (William E Deming, "On a Classification of the Problems of Statistical Inference", Journal of the American Statistical Association Vol. 37 (218), 1942)

"Data should be collected with a clear purpose in mind. Not only a clear purpose, but a clear idea as to the precise way in which they will be analysed so as to yield the desired information." (Michael J Moroney, "Facts from Figures", 1951)

"The technical analysis of any large collection of data is a task for a highly trained and expensive man who knows the mathematical theory of statistics inside and out. Otherwise the outcome is likely to be a collection of drawings - quartered pies, cute little battleships, and tapering rows of sturdy soldiers in diversified uniforms - interesting enough in the colored Sunday supplement, but hardly the sort of thing from which to draw reliable inferences." (Eric T Bell, "Mathematics: Queen and Servant of Science", 1951)

"Null hypotheses of no difference are usually known to be false before the data are collected [...] when they are, their rejection or acceptance simply reflects the size of the sample and the power of the test, and is not a contribution to science." (I Richard Savage, "Nonparametric statistics", Journal of the American Statistical Association 52, 1957)

"Philosophers of science have repeatedly demonstrated that more than one theoretical construction can always be placed upon a given collection of data." (Thomas Kuhn, "The Structure of Scientific Revolutions", 1962) 

"It has been said that data collection is like garbage collection: before you collect it you should have in mind what you are going to do with it." (Russell Fox et al, "The Science of Science", 1964)

"Measurement has too often been the leitmotif of many investigations rather than the experimental examination of hypotheses. Mounds of data are collected, which are statistically decorous and methodologically unimpeachable, but conclusions are often trivial and rarely useful in decision making. This results from an overly rigorous control of an insignificant variable and a widespread deficiency in the framing of pertinent questions. Investigators seem to have settled for what is measurable instead of measuring what they would really like to know." (Edmund D Pellegrino, "Patient Care: Mystical Research or Researchable Mystique", Clinical Research, 1964)

"If we gather more and more data and establish more and more associations, however, we will not finally find that we know something. We will simply end up having more and more data and larger sets of correlations." (Kenneth N Waltz, "Theory of International Politics Source: Theory of International Politics", 1979)

"The systematic collection of data about people has affected not only the ways in which we conceive of a society, but also the ways in which we describe our neighbour. It has profoundly transformed what we choose to do, who we try to be, and what we think of ourselves." (Ian Hacking, "The Taming of Chance", 1990)

When looking at the end result of any statistical analysis, one must be very cautious not to over interpret the data. Care must be taken to know the size of the sample, and to be certain the method for gathering information is consistent with other samples gathered. […] No one should ever base conclusions without knowing the size of the sample and how random a sample it was. But all too often such data is not mentioned when the statistics are given - perhaps it is overlooked or even intentionally omitted." (Theoni Pappas, "More Joy of Mathematics: Exploring mathematical insights & concepts", 1991)

"We do not realize how deeply our starting assumptions affect the way we go about looking for and interpreting the data we collect." (Roger A Lewin, "Kanzi: The Ape at the Brink of the Human Mind", 1994)

"The science of statistics may be described as exploring, analyzing and summarizing data; designing or choosing appropriate ways of collecting data and extracting information from them; and communicating that information. Statistics also involves constructing and testing models for describing chance phenomena. These models can be used as a basis for making inferences and drawing conclusions and, finally, perhaps for making decisions." (Fergus Daly et al, "Elements of Statistics", 1995)

"Data are collected as a basis for action. Yet before anyone can use data as a basis for action the data have to be interpreted. The proper interpretation of data will require that the data be presented in context, and that the analysis technique used will filter out the noise."  (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"Data are generally collected as a basis for action. However, unless potential signals are separated from probable noise, the actions taken may be totally inconsistent with the data. Thus, the proper use of data requires that you have simple and effective methods of analysis which will properly separate potential signals from probable noise." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"Just as dynamics arise from feedback, so too all learning depends on feedback. We make decisions that alter the real world; we gather information feedback about the real world, and using the new information we revise our understanding of the world and the decisions we make to bring our perception of the state of the system closer to our goals." (John D Sterman, "Business dynamics: Systems thinking and modeling for a complex world", 2000) 

"Without meaningful data there can be no meaningful analysis. The interpretation of any data set must be based upon the context of those data. Unfortunately, much of the data reported to executives today are aggregated and summed over so many different operating units and processes that they cannot be said to have any context except a historical one - they were all collected during the same time period. While this may be rational with monetary figures, it can be devastating to other types of data." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"Data is a fact of life. As time goes by, we collect more and more data, making our original reason for collecting the data harder to accomplish. We don't collect data just to waste time or keep busy; we collect data so that we can gain knowledge, which can be used to improve the efficiency of our organization, improve profit margins, and on and on. The problem is that as we collect more data, it becomes harder for us to use the data to derive this knowledge. We are being suffocated by this raw data, yet we need to find a way to use it." (Seth Paul et al. "Preparing and Mining Data with Microsoft SQL Server 2000 and Analysis", 2002)

"Statistics depend on collecting information. If questions go unasked, or if they are asked in ways that limit responses, or if measures count some cases but exclude others, information goes ungathered, and missing numbers result. Nevertheless, choices regarding which data to collect and how to go about collecting the information are inevitable." (Joel Best, "More Damned Lies and Statistics: How numbers confuse public issues", 2004)

"Put simply, statistics is a range of procedures for gathering, organizing, analyzing and presenting quantitative data. […] Essentially […], statistics is a scientific approach to analyzing numerical data in order to enable us to maximize our interpretation, understanding and use. This means that statistics helps us turn data into information; that is, data that have been interpreted, understood and are useful to the recipient. Put formally, for your project, statistics is the systematic collection and analysis of numerical data, in order to investigate or discover relationships among phenomena so as to explain, predict and control their occurrence." (Reva B Brown & Mark Saunders, "Dealing with Statistics: What You Need to Know", 2008)

"Statistics is the art of learning from data. It is concerned with the collection of data, their subsequent description, and their analysis, which often leads to the drawing of conclusions." (Sheldon M Ross, "Introductory Statistics" 3rd Ed., 2009)

"Statistics is the science of collecting, organizing, analyzing, and interpreting data in order to make decisions." (Ron Larson & Betsy Farber, "Elementary Statistics: Picturing the World" 5th Ed., 2011)

"The discrepancy between our mental models and the real world may be a major problem of our times; especially in view of the difficulty of collecting, analyzing, and making sense of the unbelievable amount of data to which we have access today." (Ugo Bardi, "The Limits to Growth Revisited", 2011)

"In order to be effective a descriptive statistic has to make sense - it has to distill some essential characteristic of the data into a value that is both appropriate and understandable. […] the justification for computing any given statistic must come from the nature of the data themselves - it cannot come from the arithmetic, nor can it come from the statistic. If the data are a meaningless collection of values, then the summary statistics will also be meaningless - no arithmetic operation can magically create meaning out of nonsense. Therefore, the meaning of any statistic has to come from the context for the data, while the appropriateness of any statistic will depend upon the use we intend to make of that statistic." (Donald J Wheeler, "Myths About Data Analysis", International Lean & Six Sigma Conference, 2012)

"Each systems archetype embodies a particular theory about dynamic behavior that can serve as a starting point for selecting and formulating raw data into a coherent set of interrelationships. Once those relationships are made explicit and precise, the 'theory' of the archetype can then further guide us in our data-gathering process to test the causal relationships through direct observation, data analysis, or group deliberation." (Daniel H Kim, "Systems Archetypes as Dynamic Theories", The Systems Thinker Vol. 24 (1), 2013)

"Statistics is an integral part of the quantitative approach to knowledge. The field of statistics is concerned with the scientific study of collecting, organizing, analyzing, and drawing conclusions from data." (Kandethody M Ramachandran & Chris P Tsokos, "Mathematical Statistics with Applications in R" 2nd Ed., 2015)

"The term data, unlike the related terms facts and evidence, does not connote truth. Data is descriptive, but data can be erroneous. We tend to distinguish data from information. Data is a primitive or atomic state (as in ‘raw data’). It becomes information only when it is presented in context, in a way that informs. This progression from data to information is not the only direction in which the relationship flows, however; information can also be broken down into pieces, stripped of context, and stored as data. This is the case with most of the data that’s stored in computer systems. Data that’s collected and stored directly by machines, such as sensors, becomes information only when it’s reconnected to its context."  (Stephen Few, "Signal: Understanding What Matters in a World of Noise", 2015)

"Big data is, in a nutshell, large amounts of data that can be gathered up and analyzed to determine whether any patterns emerge and to make better decisions." (Daniel Covington, Analytics: Data Science, Data Analysis and Predictive Analytics for Business, 2016)

"Statistics can be defined as a collection of techniques used when planning a data collection, and when subsequently analyzing and presenting data." (Birger S Madsen, "Statistics for Non-Statisticians", 2016)

"Statistics is the science of collecting, organizing, and interpreting numerical facts, which we call data. […] Statistics is the science of learning from data." (Moore McCabe & Alwan Craig, "The Practice of Statistics for Business and Economics" 4th Ed., 2016)

"Collecting data through sampling therefore becomes a never-ending battle to avoid sources of bias. [...] While trying to obtain a random sample, researchers sometimes make errors in judgment about whether every person or thing is equally likely to be sampled." (Daniel J Levitin, "Weaponized Lies", 2017)

"Just because there’s a number on it, it doesn’t mean that the number was arrived at properly. […] There are a host of errors and biases that can enter into the collection process, and these can lead millions of people to draw the wrong conclusions. Although most of us won’t ever participate in the collection process, thinking about it, critically, is easy to learn and within the reach of all of us." (Daniel J Levitin, "Weaponized Lies", 2017)

"Measurements must be standardized. There must be clear, replicable, and precise procedures for collecting data so that each person who collects it does it in the same way." (Daniel J Levitin, "Weaponized Lies", 2017)

"To be any good, a sample has to be representative. A sample is representative if every person or thing in the group you’re studying has an equally likely chance of being chosen. If not, your sample is biased. […] The job of the statistician is to formulate an inventory of all those things that matter in order to obtain a representative sample. Researchers have to avoid the tendency to capture variables that are easy to identify or collect data on - sometimes the things that matter are not obvious or are difficult to measure." (Daniel J Levitin, "Weaponized Lies", 2017)

[Murphy’s Laws of Analysis:] "(1) In any collection of data, the figures that are obviously correct contain errors. (2) It is customary for a decimal to be misplaced. (3) An error that can creep into a calculation, will. Also, it will always be in the direction that will cause the most damage to the calculation." (G C Deakly)

"[…] numerous samples collected without a clear idea of what is to be done with the data are commonly less useful than a moderate number of samples collected in accordance with a specific design." (William C Krumbein)

🦋Science: On Data Models (Quotes)

"Science manipulates things and gives up living in them. It makes its own limited models of things; operating upon these indices or variables to effect whatever transformations are permitted by their definition, it comes face to face with the real world only at rare intervals. Science is and always will be that admirably active, ingenious, and bold way of thinking whose fundamental bias is to treat everything as though it were an object-in-general - as though it meant nothing to us and yet was predestined for our own use." (Maurice Merleau-Ponty, "L'Œil et l'Esprit", 1960)

"For the theory-practice iteration to work, the scientist must be, as it were, mentally ambidextrous; fascinated equally on the one hand by possible meanings, theories, and tentative models to be induced from data and the practical reality of the real world, and on the other with the factual implications deducible from tentative theories, models and hypotheses." (George E P Box, "Science and Statistics", Journal of the American Statistical Association 71, 1976)

“The purpose of models is not to fit the data but to sharpen the questions.” (Samuel Karlin, 1983)

"There are those who try to generalize, synthesize, and build models, and there are those who believe nothing and constantly call for more data. The tension between these two groups is a healthy one; science develops mainly because of the model builders, yet they need the second group to keep them honest." (Andrew Miall, "Principles of Sedimentary Basin Analysis", 1984)

"Models are often used to decide issues in situations marked by uncertainty. However statistical differences from data depend on assumptions about the process which generated these data. If the assumptions do not hold, the inferences may not be reliable either. This limitation is often ignored by applied workers who fail to identify crucial assumptions or subject them to any kind of empirical testing. In such circumstances, using statistical procedures may only compound the uncertainty." (David A Greedman & William C Navidi, "Regression Models for Adjusting the 1980 Census", Statistical Science Vol. 1 (1), 1986)

"Competent scientists do not believe their own models or theories, but rather treat them as convenient fictions. […] The issue to a scientist is not whether a model is true, but rather whether there is another whose predictive power is enough better to justify movement from today's fiction to a new one." (Steve Vardeman," Comment", Journal of the American Statistical Association 82, 1987)

"[…] no good model ever accounted for all the facts, since some data was bound to be misleading if not plain wrong. A theory that did fit all the data would have been ‘carpentered’ to do this and would thus be open to suspicion." (Francis H C Crick, "What Mad Pursuit: A Personal View of Scientific Discovery", 1988)

"Information engineering has been defined with the reference to automated techniques as follows: An interlocking set of automated techniques in which enterprise models, data models and process models are built up in a comprehensive knowledge-base and are used to create and maintain data-processing systems." (James Martin, "Information Engineering, 1989)

"When evaluating a model, at least two broad standards are relevant. One is whether the model is consistent with the data. The other is whether the model is consistent with the ‘real world’." (Kenneth A Bollen, "Structural Equations with Latent Variables", 1989)

"So we pour in data from the past to fuel the decision-making mechanisms created by our models, be they linear or nonlinear. But therein lies the logician's trap: past data from real life constitute a sequence of events rather than a set of independent observations, which is what the laws of probability demand. [...] It is in those outliers and imperfections that the wildness lurks." (Peter L Bernstein, "Against the Gods: The Remarkable Story of Risk", 1996)

"Building statistical models is just like this. You take a real situation with real data, messy as this is, and build a model that works to explain the behavior of real data." (Martha Stocking, New York Times, 2000)

"The point of a model is to get useful information about the relation between the response and predictor variables. Interpretability is a way of getting information. But a model does not have to be simple to provide reliable information about the relation between predictor and response variables; neither does it have to be a data model. The goal is not interpretability, but accurate information." (Leo Breiman, "Statistical Modeling: The Two Cultures", Statistical Science Vol 16 (3), 2001)

"A smaller model with fewer covariates has two advantages: it might give better predictions than a big model and it is more parsimonious (simpler). Generally, as you add more variables to a regression, the bias of the predictions decreases and the variance increases. Too few covariates yields high bias; this called underfitting. Too many covariates yields high variance; this called overfitting. Good predictions result from achieving a good balance between bias and variance. […] fiding a good model involves trading of fit and complexity." (Larry A Wasserman, "All of Statistics: A concise course in statistical inference", 2004)

"Bayesian inference is appealing when prior information is available since Bayes’ theorem is a natural way to combine prior information with data. Some people find Bayesian inference psychologically appealing because it allows us to make probability statements about parameters. […] In parametric models, with large samples, Bayesian and frequentist methods give approximately the same inferences. In general, they need not agree." (Larry A Wasserman, "All of Statistics: A concise course in statistical inference", 2004)

"[…] studying methods for parametric models is useful for two reasons. First, there are some cases where background knowledge suggests that a parametric model provides a reasonable approximation. […] Second, the inferential concepts for parametric models provide background for understanding certain nonparametric methods." (Larry A Wasserman, "All of Statistics: A concise course in statistical inference", 2004)

"[...] construction of a data model is precisely the selective relevant depiction of the phenomena by the user of the theory required for the possibility of representation of the phenomenon."  (Bas C van Fraassen, "Scientific Representation: Paradoxes of Perspective", 2008)

"There are three possible reasons for [the] absence of predictive power. First, it is possible that the models are misspecified. Second, it is possible that the model’s explanatory factors are measured at too high a level of aggregation [...] Third, [...] the search for statistically significant relationships may not be the strategy best suited for evaluating our model’s ability to explain real world events [...] the lack of predictive power is the result of too much emphasis having been placed on finding statistically significant variables, which may be overdetermined. Statistical significance is generally a flawed way to prune variables in regression models [...] Statistically significant variables may actually degrade the predictive accuracy of a model [...] [By using] models that are constructed on the basis of pruning undertaken with the shears of statistical significance, it is quite possible that we are winnowing our models away from predictive accuracy." (Michael D Ward et al, "The perils of policy by p-value: predicting civil conflicts" Journal of Peace Research 47, 2010)

"In the predictive modeling disciplines an ensemble is a group of algorithms that is used to solve a common problem [...] Each modeling algorithm has specific strengths and weaknesses and each provides a different mathematical perspective on the relationships modeled, just like each instrument in a musical ensemble provides a different voice in the composition. Predictive modeling ensembles use several algorithms to contribute their perspectives on the prediction problem and then combine them together in some way. Usually ensembles will provide more accurate models than individual algorithms which are also more general in their ability to work well on different data sets [...] the approach has proven to yield the best results in many situations." ( Gary Miner et al, "Practical Text Mining and Statistical Analysis for Non-Structured Text Data Applications", 2012)

"Big Data processes codify the past. They do not invent the future. Doing that requires moral imagination, and that’s something only humans can provide. We have to explicitly embed better values into our algorithms, creating Big Data models that follow our ethical lead. Sometimes that will mean putting fairness ahead of profit." (Cathy O'Neil, "Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy", 2016)

"The greatest plus of data modeling is that it produces a simple and understandable picture of the relationship between the input variables and responses [...] different models, all of them equally good, may give different pictures of the relation between the predictor and response variables [...] One reason for this multiplicity is that goodness-of-fit tests and other methods for checking fit give a yes–no answer. With the lack of power of these tests with data having more than a small number of dimensions, there will be a large number of models whose fit is acceptable. There is no way, among the yes–no methods for gauging fit, of determining which is the better model." (Leo Breiman, "Statistical modeling: The two cultures" Statistical Science 16(3), 2001)

"There may be no significant difference between the point of view of inferring the true structure and that of making a prediction if an infinitely large quantity of data is available or if the data are noiseless. However, in modeling based on a finite quantity of real data, there is a significant gap between these two points of view, because an optimal model for prediction purposes may be different from one obtained by estimating the 'true model'." (Genshiro Kitagawa & Sadanori Konis, "Information Criteria and Statistical Modeling", 2007)

"Causal inference is different, because a change in the system is contemplated - an intervention. Descriptive statistics tell you about the data that you happen to have. Causal models claim to tell you what will happen to some of the numbers if you intervene to change other numbers." (David A. Freedman, "Statistical Models: Theory and Practice", 2009)

"It is important to remember that predictive data analytics models built using machine learning techniques are tools that we can use to help make better decisions within an organization and are not an end in themselves. It is paramount that, when tasked with creating a predictive model, we fully understand the business problem that this model is being constructed to address and ensure that it does address it." (John D Kelleher et al, "Fundamentals of Machine Learning for Predictive Data Analytics: Algorithms, worked examples, and case studies", 2015)

"A popular misconception holds that the era of Big Data means the end of a need for sampling. In fact, the proliferation of data of varying quality and relevance reinforces the need for sampling as a tool to work efficiently with a variety of data, and minimize bias. Even in a Big Data project, predictive models are typically developed and piloted with samples." (Peter C Bruce & Andrew G Bruce, "Statistics for Data Scientists: 50 Essential Concepts", 2016)

"Optimization is more than finding the best simulation results. It is itself a complex and evolving field that, subject to certain information constraints, allows data scientists, statisticians, engineers, and traders alike to perform reality checks on modeling results." (Chris Conlan, "Automated Trading with R: Quantitative Research and Platform Development", 2016)

"Data analysis and data mining are concerned with unsupervised pattern finding and structure determination in data sets. The data sets themselves are explicitly linked as a form of representation to an observational or otherwise empirical domain of interest. 'Structure' has long been understood as symmetry which can take many forms with respect to any transformation, including point, translational, rotational, and many others. Symmetries directly point to invariants, which pinpoint intrinsic properties of the data and of the background empirical domain of interest. As our data models change, so too do our perspectives on analysing data." (Fionn Murtagh, "Data Science Foundations: Geometry and Topology of Complex Hierarchic Systems and Big Data Analytics", 2018)

"Any fool can fit a statistical model, given the data and some software. The real challenge is to decide whether it actually fits the data adequately. It might be the best that can be obtained, but still not good enough to use." (Robert Grant, "Data Visualization: Charts, Maps and Interactive Graphics", 2019)

"Cross-validation is a useful tool for finding optimal predictive models, and it also works well in visualization. The concept is simple: split the data at random into a 'training' and a 'test' set, fit the model to the training data, then see how well it predicts the test data. As the model gets more complex, it will always fit the training data better and better. It will also start off getting better results on the test data, but there comes a point where the test data predictions start going wrong." (Robert Grant, "Data Visualization: Charts, Maps and Interactive Graphics", 2019)

🦋Science: On Noise (Quotes)

"Neither noise nor information is predictable." (Ray Kurzweil, "The Age of Spiritual Machines: When Computers Exceed Human Intelligence", 1999)

"Data are collected as a basis for action. Yet before anyone can use data as a basis for action the data have to be interpreted. The proper interpretation of data will require that the data be presented in context, and that the analysis technique used will filter out the noise."  (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"Data are generally collected as a basis for action. However, unless potential signals are separated from probable noise, the actions taken may be totally inconsistent with the data. Thus, the proper use of data requires that you have simple and effective methods of analysis which will properly separate potential signals from probable noise." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"No matter what the data, and no matter how the values are arranged and presented, you must always use some method of analysis to come up with an interpretation of the data. While every data set contains noise, some data sets may contain signals. Therefore, before you can detect a signal within any given data set, you must first filter out the noise." (Donald J Wheeler," Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"We analyze numbers in order to know when a change has occurred in our processes or systems. We want to know about such changes in a timely manner so that we can respond appropriately. While this sounds rather straightforward, there is a complication - the numbers can change even when our process does not. So, in our analysis of numbers, we need to have a way to distinguish those changes in the numbers that represent changes in our process from those that are essentially noise." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"While all data contain noise, some data contain signals. Before you can detect a signal, you must filter out the noise." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"The acquisition of information is a flow from noise to order - a process converting entropy to redundancy. During this process, the amount of information decreases but is compensated by constant re- coding. In the recoding the amount of information per unit increases by means of a new symbol which represents the total amount of the old. The maturing thus implies information condensation. Simultaneously, the redundance decreases, which render the information more difficult to interpret." (Lars Skyttner, "General Systems Theory: Ideas and Applications", 2001)

"In fact, an information theory that leaves out the issue of noise turns out to have no content." (Hans Christian von Baeyer, "Information, The New Language of Science", 2003)

"This phenomenon, common to chaos theory, is also known as sensitive dependence on initial conditions. Just a small change in the initial conditions can drastically change the long-term behavior of a system. Such a small amount of difference in a measurement might be considered experimental noise, background noise, or an inaccuracy of the equipment." (Greg Rae, Chaos Theory: A Brief Introduction, 2006)

"Data analysis is not generally thought of as being simple or easy, but it can be. The first step is to understand that the purpose of data analysis is to separate any signals that may be contained within the data from the noise in the data. Once you have filtered out the noise, anything left over will be your potential signals. The rest is just details." (Donald J Wheeler," Myths About Data Analysis", International Lean & Six Sigma Conference, 2012)

"Distinguishing the signal from the noise requires both scientific knowledge and self-knowledge." (Nate Silver, "The Signal and the Noise: Why So Many Predictions Fail-but Some Don't", 2012)

"Economists should study financial markets as they actually operate, not as they assume them to operate - observing the way in which information is actually processed, observing the serial correlations, bonanzas, and sudden stops, not assuming these away as noise around the edges of efficient and rational markets." (Adair Turner, "Economics after the Crisis: Objectives and means", 2012)

"Finding patterns is easy in any kind of data-rich environment; that's what mediocre gamblers do. The key is in determining whether the patterns represent signal or noise." (Nate Silver, "The Signal and the Noise: Why So Many Predictions Fail-but Some Don't", 2012)

"The signal is the truth. The noise is what distracts us from the truth." (Nate Silver, "The Signal and the Noise: Why So Many Predictions Fail-but Some Don't", 2012)

"A signal is a useful message that resides in data. Data that isn’t useful is noise. […] When data is expressed visually, noise can exist not only as data that doesn’t inform but also as meaningless non-data elements of the display (e.g. irrelevant attributes, such as a third dimension of depth in bars, color variation that has no significance, and artificial light and shadow effects)." (Stephen Few, "Signal: Understanding What Matters in a World of Noise", 2015)

"Data contain descriptions. Some are true, some are not. Some are useful, most are not. Skillful use of data requires that we learn to pick out the pieces that are true and useful. [...] To find signals in data, we must learn to reduce the noise - not just the noise that resides in the data, but also the noise that resides in us. It is nearly impossible for noisy minds to perceive anything but noise in data." (Stephen Few, "Signal: Understanding What Matters in a World of Noise", 2015)

"When we find data quality issues due to valid data during data exploration, we should note these issues in a data quality plan for potential handling later in the project. The most common issues in this regard are missing values and outliers, which are both examples of noise in the data." (John D Kelleher et al, "Fundamentals of Machine Learning for Predictive Data Analytics: Algorithms, worked examples, and case studies", 2015)

"Information theory leads to the quantification of the information content of the source, as denoted by entropy, the characterization of the information-bearing capacity of the communication channel, as related to its noise characteristics, and consequently the establishment of the relationship between the information content of the source and the capacity of the channel. In short, information theory provides a quantitative measure of the information contained in message signals and help determine the capacity of a communication system to transfer this information from source to sink over a noisy channel in a reliable fashion." (Ali Grami, "Information Theory", 2016)

"Repeated observations of the same phenomenon do not always produce the same results, due to random noise or error. Sampling errors result when our observations capture unrepresentative circumstances, like measuring rush hour traffic on weekends as well as during the work week. Measurement errors reflect the limits of precision inherent in any sensing device. The notion of signal to noise ratio captures the degree to which a series of observations reflects a quantity of interest as opposed to data variance. As data scientists, we care about changes in the signal instead of the noise, and such variance often makes this problem surprisingly difficult." (Steven S Skiena, "The Data Science Design Manual", 2017)

"[...] in the statistical world, what we see and measure around us can be considered as the sum of a systematic mathematical idealized form plus some random contribution that cannot yet be explained. This is the classic idea of the signal and the noise." (David Spiegelhalter, "The Art of Statistics: Learning from Data", 2019)

🦋Science: On Context (Quotes)

 "Some of the common ways of producing a false statistical argument are to quote figures without their context, omitting the cautions as to their incompleteness, or to apply them to a group of phenomena quite different to that to which they in reality relate; to take these estimates referring to only part of a group as complete; to enumerate the events favorable to an argument, omitting the other side; and to argue hastily from effect to cause, this last error being the one most often fathered on to statistics. For all these elementary mistakes in logic, statistics is held responsible." (Sir Arthur L Bowley, "Elements of Statistics", 1901)

"When evaluating the reliability and generality of data, it is often important to know the aims of the experimenter. When evaluating the importance of experimental results, however, science has a trick of disregarding the experimenter's rationale and finding a more appropriate context for the data than the one he proposed." (Murray Sidman, "Tactics of Scientific Research", 1960)

"Data in isolation are meaningless, a collection of numbers. Only in context of a theory do they assume significance […]" (George Greenstein, "Frozen Star" , 1983)

"Graphics must not quote data out of context." (Edward R Tufte, "The Visual Display of Quantitative Information", 1983)

"The problem solver needs to stand back and examine problem contexts in the light of different 'Ws' (Weltanschauungen). Perhaps he can then decide which 'W' seems to capture the essence of the particular problem context he is faced with. This whole process needs formalizing if it is to be carried out successfully. The problem solver needs to be aware of different paradigms in the social sciences, and he must be prepared to view the problem context through each of these paradigms." (Michael C Jackson, "Towards a System of Systems Methodologies", 1984)

"It is commonly said that a pattern, however it is written, has four essential parts: a statement of the context where the pattern is useful, the problem that the pattern addresses, the forces that play in forming a solution, and the solution that resolves those forces. [...] it supports the definition of a pattern as 'a solution to a problem in a context', a definition that [unfortunately] fixes the bounds of the pattern to a single problem-solution pair." (Martin Fowler, "Analysis Patterns: Reusable Object Models", 1997)

"We do not learn much from looking at a model - we learn more from building the model and manipulating it. Just as one needs to use or observe the use of a hammer in order to really understand its function, similarly, models have to be used before they will give up their secrets. In this sense, they have the quality of a technology - the power of the model only becomes apparent in the context of its use." (Margaret Morrison & Mary S Morgan, "Models as mediating instruments", 1999)

"Data are collected as a basis for action. Yet before anyone can use data as a basis for action the data have to be interpreted. The proper interpretation of data will require that the data be presented in context, and that the analysis technique used will filter out the noise."  (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"[…] you simply cannot make sense of any number without a contextual basis. Yet the traditional attempts to provide this contextual basis are often flawed in their execution. [...] Data have no meaning apart from their context. Data presented without a context are effectively rendered meaningless." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"All scientific theories, even those in the physical sciences, are developed in a particular cultural context. Although the context may help to explain the persistence of a theory in the face of apparently falsifying evidence, the fact that a theory arises from a particular context is not sufficient to condemn it. Theories and paradigms must be accepted, modified or rejected on the basis of evidence." (Richard P Bentall,  "Madness Explained: Psychosis and Human Nature", 2003)

"Mathematical modeling is as much ‘art’ as ‘science’: it requires the practitioner to (i) identify a so-called ‘real world’ problem (whatever the context may be); (ii) formulate it in mathematical terms (the ‘word problem’ so beloved of undergraduates); (iii) solve the problem thus formulated (if possible; perhaps approximate solutions will suffice, especially if the complete problem is intractable); and (iv) interpret the solution in the context of the original problem." (John A Adam, "Mathematics in Nature", 2003)

"Context is not as simple as being in a different space [...] context includes elements like our emotions, recent experiences, beliefs, and the surrounding environment - each element possesses attributes, that when considered in a certain light, informs what is possible in the discussion." (George Siemens, "Knowing Knowledge", 2006)

"Statistics can certainly pronounce a fact, but they cannot explain it without an underlying context, or theory. Numbers have an unfortunate tendency to supersede other types of knowing. […] Numbers give the illusion of presenting more truth and precision than they are capable of providing." (Ronald J Baker, "Measure what Matters to Customers: Using Key Predictive Indicators", 2006)

"Mostly we rely on stories to put our ideas into context and give them meaning. It should be no surprise, then, that the human capacity for storytelling plays an important role in the intrinsically human-centered approach to problem solving, design thinking." (Tim Brown, "Change by Design: How Design Thinking Transforms Organizations and Inspires Innovation", 2009)

"Context (information that lends to better understanding the who, what, when, where, and why of your data) can make the data clearer for readers and point them in the right direction. At the least, it can remind you what a graph is about when you come back to it a few months later. […] Context helps readers relate to and understand the data in a visualization better. It provides a sense of scale and strengthens the connection between abstract geometry and colors to the real world." (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"Readability in visualization helps people interpret data and make conclusions about what the data has to say. Embed charts in reports or surround them with text, and you can explain results in detail. However, take a visualization out of a report or disconnect it from text that provides context (as is common when people share graphics online), and the data might lose its meaning; or worse, others might misinterpret what you tried to show." (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"The data is a simplification - an abstraction - of the real world. So when you visualize data, you visualize an abstraction of the world, or at least some tiny facet of it. Visualization is an abstraction of data, so in the end, you end up with an abstraction of an abstraction, which creates an interesting challenge. […] Just like what it represents, data can be complex with variability and uncertainty, but consider it all in the right context, and it starts to make sense." (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"Without context, data is useless, and any visualization you create with it will also be useless. Using data without knowing anything about it, other than the values themselves, is like hearing an abridged quote secondhand and then citing it as a main discussion point in an essay. It might be okay, but you risk finding out later that the speaker meant the opposite of what you thought."  (Nathan Yau, "Data Points: Visualization That Means Something", 2013)

"Statistics are meaningless unless they exist in some context. One reason why the indicators have become more central and potent over time is that the longer they have been kept, the easier it is to find useful patterns and points of reference." (Zachary Karabell, "The Leading Indicators: A short history of the numbers that rule our world", 2014)

"The term data, unlike the related terms facts and evidence, does not connote truth. Data is descriptive, but data can be erroneous. We tend to distinguish data from information. Data is a primitive or atomic state (as in ‘raw data’). It becomes information only when it is presented in context, in a way that informs. This progression from data to information is not the only direction in which the relationship flows, however; information can also be broken down into pieces, stripped of context, and stored as data. This is the case with most of the data that’s stored in computer systems. Data that’s collected and stored directly by machines, such as sensors, becomes information only when it’s reconnected to its context."  (Stephen Few, "Signal: Understanding What Matters in a World of Noise", 2015)

"Infographics combine art and science to produce something that is not unlike a dashboard. The main difference from a dashboard is the subjective data and the narrative or story, which enhances the data-driven visual and engages the audience quickly through highlighting the required context." (Travis Murphy, "Infographics Powered by SAS®: Data Visualization Techniques for Business Reporting", 2018)

🦋Science: On Experiment (Quotes)

"Those who have not imbibed the prejudices of philosophers, are easily convinced that natural knowledge is to be founded on experiment and observation." (Colin Maclaurin, "An Account of Sir Isaac Newton’s Philosophical Discoveries", 1748)

"We have three principal means: observation of nature, reflection, and experiment. Observation gathers the facts reflection combines them, experiment verifies the result of the combination. It is essential that the observation of nature be assiduous, that reflection be profound, and that experimentation be exact. Rarely does one see these abilities in combination. And so, creative geniuses are not common." (Denis Diderot, "On the Interpretation of Nature", 1753)

"Facts, observations, experiments - these are the materials of a great edifice, but in assembling them we must combine them into classes, distinguish which belongs to which order and to which part of the whole each pertains." (Antoine L Lavoisier, "Mémoires de l’Académie Royale des Sciences", 1777)

"The art of drawing conclusions from experiments and observations consists in evaluating probabilities and in estimating whether they are sufficiently great or numerous enough to constitute proofs. This kind of calculation is more complicated and more difficult than it is commonly thought to be […]" (Antoine-Laurent Lavoisier, cca. 1790)

"We must trust to nothing but facts: These are presented to us by Nature, and cannot deceive. We ought, in every instance, to submit our reasoning to the test of experiment, and never to search for truth but by the natural road of experiment and observation." (Antoin-Laurent de Lavoisiere, "Elements of Chemistry", 1790)

"Conjecture may lead you to form opinions, but it cannot produce knowledge. Natural philosophy must be built upon the phenomena of nature discovered by observation and experiment." (George Adams, "Lectures on Natural and Experimental Philosophy" Vol. 1, 1794)

"[Precision] is the very soul of science; and its attainment afford the only criterion, or at least the best, of the truth of theories, and the correctness of experiments." (John F W Herschel, "A Preliminary Discourse on the Study of Natural Philosophy", 1830)

"The hypothesis, by suggesting observations and experiments, puts us upon the road to that independent evidence if it be really attainable; and till it be attained, the hypothesis ought not to count for more than a suspicion." (John S Mill, "A System of Logic, Ratiocinative and Inductive", 1843)

"The framing of hypotheses is, for the enquirer after truth, not the end, but the beginning of his work. Each of his systems is invented, not that he may admire it and follow it into all its consistent consequences, but that he may make it the occasion of a course of active experiment and observation. And if the results of this process contradict his fundamental assumptions, however ingenious, however symmetrical, however elegant his system may be, he rejects it without hesitation. He allows no natural yearning for the offspring of his own mind to draw him aside from the higher duty of loyalty to his sovereign, Truth, to her he not only gives his affections and his wishes, but strenuous labour and scrupulous minuteness of attention." (William Whewell, "Philosophy of the Inductive Sciences" Vol. 2, 1847)

"An anticipative idea or an hypothesis is, then, the necessary starting point for all experimental reasoning. Without it, we could not make any investigation at all nor learn anything; we could only pile up sterile observations. If we experiment without a preconceived idea, we should move at random […]" (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"Isolated facts and experiments have in themselves no value, however great their number may be. They only become valuable in a theoretical or practical point of view when they make us acquainted with the law of a series of uniformly recurring phenomena, or, it may be, only give a negative result showing an incompleteness in our knowledge of such a law, till then held to be perfect." (Hermann von Helmholtz, "The Aim and Progress of Physical Science", 1869)

"It is surprising to learn the number of causes of error which enter into the simplest experiment, when we strive to attain rigid accuracy." (William S Jevons, "The Principles of Science: A Treatise on Logic and Scientific Method", 1874)

"A discoverer is a tester of scientific ideas; he must not only be able to imagine likely hypotheses, and to select suitable ones for investigation, but, as hypotheses may be true or untrue, he must also be competent to invent appropriate experiments for testing them, and to devise the requisite apparatus and arrangements." (George Gore, "The Art of Scientific Discovery", 1878)

"Even one well-made observation will be enough in many cases, just as one well-constructed experiment often suffices for the establishment of a law." (Émile Durkheim, "The Rules of Sociological Method", "The Rules of Sociological Method", 1895)

"Every experiment, every observation has, besides its immediate result, effects which, in proportion to its value, spread always on all sides into ever distant parts of knowledge." (Sir Michael Foster, "Annual Report of the Board of Regents of the Smithsonian Institution", 1898)

"If the number of experiments be very large, we may have precise information as to the value of the mean, but if our sample be small, we have two sources of uncertainty: (I) owing to the 'error of random sampling' the mean of our series of experiments deviates more or less widely from the mean of the population, and (2) the sample is not sufficiently large to determine what is the law of distribution of individuals." William S Gosset, "The Probable Error of a Mean", Biometrika, 1908)

"An experiment is an observation that can be repeated, isolated and varied. The more frequently you can repeat an observation, the more likely are you to see clearly what is there and to describe accurately what you have seen. The more strictly you can isolate an observation, the easier does your task of observation become, and the less danger is there of your being led astray by irrelevant circumstances, or of placing emphasis on the wrong point. The more widely you can vary an observation, the more clearly will be the uniformity of experience stand out, and the better is your chance of discovering laws." (Edward B Titchener, "A Text-Book of Psychology", 1909)

"Theory is the best guide for experiment - that were it not for theory and the problems and hypotheses that come out of it, we would not know the points we wanted to verify, and hence would experiment aimlessly" (Henry Hazlitt,  "Thinking as a Science", 1916)

"A scientist, whether theorist or experimenter, puts forward statements, or systems of statements, and tests them step by step. In the field of the empirical sciences, more particularly, he constructs hypotheses, or systems of theories, and tests them against experience by observation and experiment." (Karl Popper, "The Logic of Scientific Discovery", 1934)

"While it is true that theory often sets difficult, if not impossible tasks for the experiment, it does, on the other hand, often lighten the work of the experimenter by disclosing cogent relationships which make possible the indirect determination of inaccessible quantities and thus render difficult measurements unnecessary." (Georg Joos, "Theoretical Physics", 1934)

"In relation to any experiment we may speak of this hypothesis as the null hypothesis, and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis." (Ronald Fisher, "The Design of Experiments", 1935)

"Statistics is a scientific discipline concerned with collection, analysis, and interpretation of data obtained from observation or experiment. The subject has a coherent structure based on the theory of Probability and includes many different procedures which contribute to research and development throughout the whole of Science and Technology." (Egon Pearson, 1936)

"Experiment as compared with mere observation has some of the characteristics of cross-examining nature rather than merely overhearing her." (Alan Gregg, "The Furtherance of Medical Research", 1941)

"The well-known virtue of the experimental method is that it brings situational variables under tight control. It thus permits rigorous tests of hypotheses and confidential statements about causation. The correlational method, for its part, can study what man has not learned to control. Nature has been experimenting since the beginning of time, with a boldness and complexity far beyond the resources of science. The correlator’s mission is to observe and organize the data of nature’s experiments." (Lee J Cronbach, "The Two Disciplines of Scientific Psychology", The American Psychologist Vol. 12, 1957)

"A satisfactory prediction of the sequential properties of learning data from a single experiment is by no means a final test of a model. Numerous other criteria - and some more demanding - can be specified. For example, a model with specific numerical parameter values should be invariant to changes in independent variables that explicitly enter in the model." (Robert R Bush & Frederick Mosteller,"A Comparison of Eight Models?", Studies in Mathematical Learning Theory, 1959)

"Mathematical statistics provides an exceptionally clear example of the relationship between mathematics and the external world. The external world provides the experimentally measured distribution curve; mathematics provides the equation (the mathematical model) that corresponds to the empirical curve. The statistician may be guided by a thought experiment in finding the corresponding equation." (Marshall J Walker, "The Nature of Scientific Thought", 1963)

"Observation, reason, and experiment make up what we call the scientific method. (Richard Feynman, "Mainly mechanics, radiation, and heat", 1963)

"Science consists simply of the formulation and testing of hypotheses based on observational evidence; experiments are important where applicable, but their function is merely to simplify observation by imposing controlled conditions." (Henry L Batten, "Evolution of the Earth", 1971)

"In moving from conjecture to experimental data, (D), experiments must be designed which make best use of the experimenter's current state of knowledge and which best illuminate his conjecture. In moving from data to modified conjecture, (A), data must be analyzed so as to accurately present information in a manner which is readily understood by the experimenter." (George E P Box & George C Tjao, "Bayesian Inference in Statistical Analysis", 1973)

"Statistical methods are tools of scientific investigation. Scientific investigation is a controlled learning process in which various aspects of a problem are illuminated as the study proceeds. It can be thought of as a major iteration within which secondary iterations occur. The major iteration is that in which a tentative conjecture suggests an experiment, appropriate analysis of the data so generated leads to a modified conjecture, and this in turn leads to a new experiment, and so on." (George E P Box & George C Tjao, "Bayesian Inference in Statistical Analysis", 1973)

"A hypothesis is empirical or scientific only if it can be tested by experience. […] A hypothesis or theory which cannot be, at least in principle, falsified by empirical observations and experiments does not belong to the realm of science." (Francisco J Ayala, "Biological Evolution: Natural Selection or Random Walk", American Scientist, 1974)

"An experiment is a failure only when it also fails adequately to test the hypothesis in question, when the data it produces don't prove anything one way or the other." (Robert M Pirsig, "Zen and the Art of Motorcycle Maintenance", 1974)

"The point is that every experiment involves an error, the magnitude of which is not known beforehand and it varies from one experiment to another. For this reason, no matter what finite number of experiments have been carried out, the arithmetic mean of the values obtained will contain an error. Of course, if the experiments are conducted under identical conditions and the errors are random errors, then the error of the mean will diminish as the number of experiments is increased, but it cannot be reduced to zero for a finite number of experiments. […] The choice of entities for an experiment must be perfectly random, so that even an apparently inessential cause could not lead to erroneous conclusions." (Yakov Khurgin, "Did You Say Mathematics?", 1974)

"The essential function of a hypothesis consists in the guidance it affords to new observations and experiments, by which our conjecture is either confirmed or refuted." (Ernst Mach, "Knowledge and Error: Sketches on the Psychology of Enquiry", 1976)

"Theoretical scientists, inching away from the safe and known, skirting the point of no return, confront nature with a free invention of the intellect. They strip the discovery down and wire it into place in the form of mathematical models or other abstractions that define the perceived relation exactly. The now-naked idea is scrutinized with as much coldness and outward lack of pity as the naturally warm human heart can muster. They try to put it to use, devising experiments or field observations to test its claims. By the rules of scientific procedure it is then either discarded or temporarily sustained. Either way, the central theory encompassing it grows. If the abstractions survive they generate new knowledge from which further exploratory trips of the mind can be planned. Through the repeated alternation between flights of the imagination and the accretion of hard data, a mutual agreement on the workings of the world is written, in the form of natural law." (Edward O Wilson, "Biophilia", 1984)

"The only touchstone for empirical truth is experiment and observation." (Heinz Pagels, "Perfect Symmetry: The Search for the Beginning of Time", 1985)

"Any physical theory is always provisional, in the sense that it is only a hypothesis: you can never prove it. No matter how many times the results of experiments agree with some theory, you can never be sure that the next time the result will not contradict the theory." (Stephen Hawking,  "A Brief History of Time", 1988)

"Scientists use mathematics to build mental universes. They write down mathematical descriptions - models - that capture essential fragments of how they think the world behaves. Then they analyse their consequences. This is called 'theory'. They test their theories against observations: this is called 'experiment'. Depending on the result, they may modify the mathematical model and repeat the cycle until theory and experiment agree. Not that it's really that simple; but that's the general gist of it, the essence of the scientific method." (Ian Stewart & Martin Golubitsky, "Fearful Symmetry: Is God a Geometer?", 1992)

"Clearly, science is not simply a matter of observing facts. Every scientific theory also expresses a worldview. Philosophical preconceptions determine where facts are sought, how experiments are designed, and which conclusions are drawn from them." (Nancy R Pearcey & Charles B. Thaxton, "The Soul of Science: Christian Faith and Natural Philosophy", 1994)

"Probability theory is an ideal tool for formalizing uncertainty in situations where class frequencies are known or where evidence is based on outcomes of a sufficiently long series of independent random experiments. Possibility theory, on the other hand, is ideal for formalizing incomplete information expressed in terms of fuzzy propositions." (George Klir, "Fuzzy sets and fuzzy logic", 1995)

"The methods of science include controlled experiments, classification, pattern recognition, analysis, and deduction. In the humanities we apply analogy, metaphor, criticism, and (e)valuation. In design we devise alternatives, form patterns, synthesize, use conjecture, and model solutions." (Béla H Bánáthy, "Designing Social Systems in a Changing World", 1996)

"[…] because observations are all we have, we take them seriously. We choose hard data and the framework of mathematics as our guides, not unrestrained imagination or unrelenting skepticism, and seek the simplest yet most wide-reaching theories capable of explaining and predicting the outcome of today’s and future experiments." (Brian Greene, "The Fabric of the Cosmos", 2004)

"In science, for a theory to be believed, it must make a prediction - different from those made by previous theories - for an experiment not yet done. For the experiment to be meaningful, we must be able to get an answer that disagrees with that prediction. When this is the case, we say that a theory is falsifiable - vulnerable to being shown false. The theory also has to be confirmable, it must be possible to verify a new prediction that only this theory makes. Only when a theory has been tested and the results agree with the theory do we advance the statement to the rank of a true scientific theory." (Lee Smolin, "The Trouble with Physics", 2006)

"The ultimate arbiter of truth is experiment, not the comfort one derives from one's a priori beliefs, nor the beauty or elegance one ascribes to one's theoretical models." (Lawrence M Krauss, "A Universe from Nothing: Why There Is Something Rather than Nothing", 2012)

"Self-selection bias occurs when people choose to be in the data - for example, when people choose to go to college, marry, or have children. […] Self-selection bias is pervasive in 'observational data', where we collect data by observing what people do. Because these people chose to do what they are doing, their choices may reflect who they are. This self-selection bias could be avoided with a controlled experiment in which people are randomly assigned to groups and told what to do." (Gary Smith, "Standard Deviations", 2014)

"We encounter regression in many contexts - pretty much whenever we see an imperfect measure of what we are trying to measure. Standardized tests are obviously an imperfect measure of ability. [...] Each experimental score is an imperfect measure of 'ability', the benefits from the layout. To the extent there is randomness in this experiment - and there surely is - the prospective benefits from the layout that has the highest score are probably closer to the mean than was the score." (Gary Smith, "Standard Deviations", 2014)

"Observation and experiment, without a rational hypothesis, is like a man groping at objects at random with his eyes shut." (Henry P Tappan, "Elements of Logic", 2015)

"The dialectical interplay of experiment and theory is a key driving force of modern science. Experimental data do only have meaning in the light of a particular model or at least a theoretical background. Reversely theoretical considerations may be logically consistent as well as intellectually elegant: Without experimental evidence they are a mere exercise of thought no matter how difficult they are. Data analysis is a connector between experiment and theory: Its techniques advise possibilities of model extraction as well as model testing with experimental data." (Achim Zielesny, "From Curve Fitting to Machine Learning" 2^nd Ed., 2016)

"If your experiment needs statistics, you ought to have done a better experiment." (Ernest Rutherford)

🦋Science: On Data Analysis (Quotes)

"As in Mathematics, so in Natural Philosophy, the Investigation of difficult Things by the Method of Analysis, ought ever to precede the Method of Composition. This Analysis consists in making Experiments and Observations, and in drawing general Conclusions from them by Induction, and admitting of no Objections against the Conclusions but such as are taken from Experiments, or other certain Truths." (Sir Isaac Newton, "Opticks", 1704)

"The errors which arise from the absence of facts are far more numerous and more durable than those which result from unsound reasoning respecting true data." (Charles Babbage, "On the Economy of Machinery and Manufactures", 1832)

"In every branch of knowledge the progress is proportional to the amount of facts on which to build, and therefore to the facility of obtaining data." (James C Maxwell, [letter to Lewis Campbell] 1851)

"Not even the most subtle and skilled analysis can overcome completely the unreliability of basic data." (Roy D G Allen, "Statistics for Economists", 1951)

"The technical analysis of any large collection of data is a task for a highly trained and expensive man who knows the mathematical theory of statistics inside and out. Otherwise the outcome is likely to be a collection of drawings - quartered pies, cute little battleships, and tapering rows of sturdy soldiers in diversified uniforms - interesting enough in the colored Sunday supplement, but hardly the sort of thing from which to draw reliable inferences." (Eric T Bell, "Mathematics: Queen and Servant of Science", 1951)

"If data analysis is to be well done, much of it must be a matter of judgment, and ‘theory’ whether statistical or non-statistical, will have to guide, not command." (John W Tukey, "The Future of Data Analysis", Annals of Mathematical Statistics, Vol. 33 (1), 1962)

"The most important maxim for data analysis to heed, and one which many statisticians seem to have shunned is this: ‘Far better an approximate answer to the right question, which is often vague, than an exact answer to the wrong question, which can always be made precise.’ Data analysis must progress by approximate answers, at best, since its knowledge of what the problem really is will at best be approximate." (John W Tukey, "The Future of Data Analysis", Annals of Mathematical Statistics, Vol. 33, No. 1, 1962)

"Statistical methods are tools of scientific investigation. Scientific investigation is a controlled learning process in which various aspects of a problem are illuminated as the study proceeds. It can be thought of as a major iteration within which secondary iterations occur. The major iteration is that in which a tentative conjecture suggests an experiment, appropriate analysis of the data so generated leads to a modified conjecture, and this in turn leads to a new experiment, and so on." (George E P Box & George C Tjao, "Bayesian Inference in Statistical Analysis", 1973)

"[...] be wary of analysts that try to quantify the unquantifiable." (Ralph Keeney & Raiffa Howard, "Decisions with Multiple Objectives: Preferences and Value Trade-offs", 1976)

"The fact must be expressed as data, but there is a problem in that the correct data is difficult to catch. So that I always say 'When you see the data, doubt it!' 'When you see the measurement instrument, doubt it!' [...]For example, if the methods such as sampling, measurement, testing and chemical analysis methods were incorrect, data. […] to measure true characteristics and in an unavoidable case, using statistical sensory test and express them as data." (Kaoru Ishikawa, Annual Quality Congress Transactions, 1981)

“Data in isolation are meaningless, a collection of numbers. Only in context of a theory do they assume significance […]” (George Greenstein, “Frozen Star”, 1983)

"[…] data analysis in the context of basic mathematical concepts and skills. The ability to use and interpret simple graphical and numerical descriptions of data is the foundation of numeracy […] Meaningful data aid in replacing an emphasis on calculation by the exercise of judgement and a stress on interpreting and communicating results." (David S Moore, "Statistics for All: Why, What and How?", 1990)

"90 percent of all problems can be solved by using the techniques of data stratification, histograms, and control charts. Among the causes of nonconformance, only one-fifth or less are attributable to the workers." (Kaoru Ishikawa, The Quality Management Journal Vol. 1, 1993)

"Science is not impressed with a conglomeration of data. It likes carefully constructed analysis of each problem." (Daniel E Koshland Jr, Science Vol. 263 (5144), [editorial] 1994)

"So we pour in data from the past to fuel the decision-making mechanisms created by our models, be they linear or nonlinear. But therein lies the logician's trap: past data from real life constitute a sequence of events rather than a set of independent observations, which is what the laws of probability demand. [...] It is in those outliers and imperfections that the wildness lurks." (Peter L Bernstein, "Against the Gods: The Remarkable Story of Risk", 1996)

"Data are generally collected as a basis for action. However, unless potential signals are separated from probable noise, the actions taken may be totally inconsistent with the data. Thus, the proper use of data requires that you have simple and effective methods of analysis which will properly separate potential signals from probable noise." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"No matter what the data, and no matter how the values are arranged and presented, you must always use some method of analysis to come up with an interpretation of the data.

While every data set contains noise, some data sets may contain signals. Therefore, before you can detect a signal within any given data set, you must first filter out the noise." (Donald J Wheeler," Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"The purpose of analysis is insight. The best analysis is the simplest analysis which provides the needed insight." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"Without meaningful data there can be no meaningful analysis. The interpretation of any data set must be based upon the context of those data." (Donald J Wheeler, "Understanding Variation: The Key to Managing Chaos" 2nd Ed., 2000)

"Put simply, statistics is a range of procedures for gathering, organizing, analyzing and presenting quantitative data. […] Essentially […], statistics is a scientific approach to analyzing numerical data in order to enable us to maximize our interpretation, understanding and use. This means that statistics helps us turn data into information; that is, data that have been interpreted, understood and are useful to the recipient. Put formally, for your project, statistics is the systematic collection and analysis of numerical data, in order to investigate or discover relationships among phenomena so as to explain, predict and control their occurrence." (Reva B Brown & Mark Saunders, "Dealing with Statistics: What You Need to Know", 2008)

"Data analysis is careful thinking about evidence." (Michael Milton, "Head First Data Analysis", 2009)

"Doing data analysis without explicitly defining your problem or goal is like heading out on a road trip without having decided on a destination." (Michael Milton, "Head First Data Analysis", 2009)

"The discrepancy between our mental models and the real world may be a major problem of our times; especially in view of the difficulty of collecting, analyzing, and making sense of the unbelievable amount of data to which we have access today." (Ugo Bardi, "The Limits to Growth Revisited", 2011)

"Data analysis is not generally thought of as being simple or easy, but it can be. The first step is to understand that the purpose of data analysis is to separate any signals that may be contained within the data from the noise in the data. Once you have filtered out the noise, anything left over will be your potential signals. The rest is just details." (Donald J Wheeler," Myths About Data Analysis", International Lean & Six Sigma Conference, 2012)

"The four questions of data analysis are the questions of description, probability, inference, and homogeneity. Any data analyst needs to know how to organize and use these four questions in order to obtain meaningful and correct results. [...] 

THE DESCRIPTION QUESTION: Given a collection of numbers, are there arithmetic values that will summarize the information contained in those numbers in some meaningful way?

THE PROBABILITY QUESTION: Given a known universe, what can we say about samples drawn from this universe? [...] 

THE INFERENCE QUESTION: Given an unknown universe, and given a sample that is known to have been drawn from that unknown universe, and given that we know everything about the sample, what can we say about the unknown universe? [...] 

THE HOMOGENEITY QUESTION: Given a collection of observations, is it reasonable to assume that they came from one universe, or do they show evidence of having come from multiple universes?" (Donald J Wheeler," Myths About Data Analysis", International Lean & Six Sigma Conference, 2012)

"Each systems archetype embodies a particular theory about dynamic behavior that can serve as a starting point for selecting and formulating raw data into a coherent set of interrelationships. Once those relationships are made explicit and precise, the 'theory' of the archetype can then further guide us in our data-gathering process to test the causal relationships through direct observation, data analysis, or group deliberation." (Daniel H Kim, "Systems Archetypes as Dynamic Theories", The Systems Thinker Vol. 24 (1), 2013)

"Statistics is an integral part of the quantitative approach to knowledge. The field of statistics is concerned with the scientific study of collecting, organizing, analyzing, and drawing conclusions from data." (Kandethody M Ramachandran & Chris P Tsokos, "Mathematical Statistics with Applications in R" 2nd Ed., 2015)

"The dialectical interplay of experiment and theory is a key driving force of modern science. Experimental data do only have meaning in the light of a particular model or at least a theoretical background. Reversely theoretical considerations may be logically consistent as well as intellectually elegant: Without experimental evidence they are a mere exercise of thought no matter how difficult they are. Data analysis is a connector between experiment and theory: Its techniques advise possibilities of model extraction as well as model testing with experimental data." (Achim Zielesny, "From Curve Fitting to Machine Learning" 2^nd Ed., 2016)

"Data analysis and data mining are concerned with unsupervised pattern finding and structure determination in data sets. The data sets themselves are explicitly linked as a form of representation to an observational or otherwise empirical domain of interest. 'Structure' has long been understood as symmetry which can take many forms with respect to any transformation, including point, translational, rotational, and many others. Symmetries directly point to invariants, which pinpoint intrinsic properties of the data and of the background empirical domain of interest. As our data models change, so too do our perspectives on analysing data." (Fionn Murtagh, "Data Science Foundations: Geometry and Topology of Complex Hierarchic Systems and Big Data Analytics", 2018)

[Murphy’s Laws of Analysis:] "(1) In any collection of data, the figures that are obviously correct contain errors. (2) It is customary for a decimal to be misplaced. (3) An error that can creep into a calculation, will. Also, it will always be in the direction that will cause the most damage to the calculation." (G C Deakly)

"We must include in any language with which we hope to describe complex data-processing situations the capability for describing data. We must also include a mechanism for determining the priorities to be applied to the data. These priorities are not fixed and are indicated in many cases by the data." (Grace Hopper) 

🦋Science: On Conjecture (Quotes)

"In the discovery of hidden things and the investigation of hidden causes, stronger reasons are obtained from sure experiments and demonstrated arguments than from probable conjectures and the opinions of philosophical speculators of the common sort […]" (William Gilbert, "De Magnete", 1600)

"The art of discovering the causes of phenomena, or true hypothesis, is like the art of deciphering, in which an ingenious conjecture greatly shortens the road." (Gottfried W Leibniz, "New Essays Concerning Human Understanding", 1704 [published 1765])

"We define the art of conjecture, or stochastic art, as the art of evaluating as exactly as possible the probabilities of things, so that in our judgments and actions we can always base ourselves on what has been found to be the best, the most appropriate, the most certain, the best advised; this is the only object of the wisdom of the philosopher and the prudence of the statesman." (Jacob Bernoulli, "Ars Conjectandi", 1713)

"One of the most intimate of all associations in the human mind is that of cause and effect. They suggest one another with the utmost readiness upon all occasions; so that it is almost impossible to contemplate the one, without having some idea of, or forming some conjecture about the other." (Joseph Priestley, "The History and Present State of Electricity", 1767)

"On the other hand, if we add observation to observation, without attempting to draw no only certain conclusions, but also conjectural views from them, we offend against the very end for which only observations ought to be made." (Friedrich W Herschel, "On the Construction of the Heavens", Philosophical Transactions of the Royal Society of London Vol. LXXV, 1785)

"Conjecture may lead you to form opinions, but it cannot produce knowledge. Natural philosophy must be built upon the phenomena of nature discovered by observation and experiment." (George Adams, "Lectures on Natural and Experimental Philosophy" Vol. 1, 1794)

"Conjectures in philosophy are termed hypotheses or theories; and the investigation of an hypothesis founded on some slight probability, which accounts for many appearances in nature, has too often been considered as the highest attainment of a philosopher. If the hypothesis (sic) hangs well together, is embellished with a lively imagination, and serves to account for common appearances - it is considered by many, as having all the qualities that should recommend it to our belief, and all that ought to be required in a philosophical system." (George Adams, "Lectures on Natural and Experimental Philosophy" Vol. 1, 1794)

"We know the effects of many things, but the causes of few; experience, therefore, is a surer guide than imagination, and inquiry than conjecture." (Charles C Colton, "Lacon", 1820)

"Life is not the object of Science: we see a little, very little; And what is beyond we can only conjecture." (Samuel Johnson, "Causes Which Produce Diversity of Opinion", 1840)

"The philosophical study of nature rises above the requirements of mere delineation, and does not consist in the sterile accumulation of isolated facts. The active and inquiring spirit of man may therefore be occasionally permitted to escape from the present into the domain of the past, to conjecture that which cannot yet be clearly determined, and thus to revel amid the ancient and ever-recurring myths [...]." (Alexander von Humboldt, "Views of Nature: Or Contemplation of the Sublime Phenomena of Creation", 1850)

"The rules of scientific investigation always require us, when we enter the domains of conjecture, to adopt that hypothesis by which the greatest number of known facts and phenomena may be reconciled." (Matthew F Maury, "The Physical Geography of the Sea", 1855)

"There is something fascinating about science. One gets such wholesale returns of conjecture out of such a trifling investment of fact." (Samuel L Clemens [Mark Twain], "Life on the Mississippi", 1883)

"It is best to prove things by actual experiment; then you know; whereas if you depend on guessing and supposing and conjecturing, you will never get educated."  (Samuel L Clemens [Mark Twain], "Eve’s Diary", 1906)

"Scientific theories are not the digest of observations, but they are inventions - conjectures boldly put forward for trial, to be eliminated if they clashed with observations; with observations which were rarely accidental, but as a rule undertaken with the definite intention of testing a theory by obtaining, if possible, a decisive refutation." (Karl R Popper, "Conjectures and Refutations: The Growth of Scientific Knowledge", 1963)

"We wish to see [...] the typical attitude of the scientist who uses mathematics to understand the world around us [...] In the solution of a problem [...] there are typically three phases. The first phase is entirely or almost entirely a matter of physics; the third, a matter of mathematics; and the intermediate phase, a transition from physics to mathematics. The first phase is the formulation of the physical hypothesis or conjecture; the second, its translation into equations; the third, the solution of the equations. Each phase calls for a different kind of work and demands a different attitude." (George Pólya, "Mathematical Methods in Science", 1963) 

"We defined the art of conjecture, or stochastic art, as the art of evaluating as exactly as possible the probabilities of things, so that in our judgments and actions we can always base ourselves on what has been found to be the best, the most appropriate, the most certain, the best advised; this is the only object of the wisdom of the philosopher and the prudence of the statesman." (Bertrand de Jouvenel, "The Art of Conjecture", 1967)

"All advances of scientific understanding, at every level, begin with a speculative adventure, an imaginative preconception of what might be true.[...] [This] conjecture is then exposed to criticism to find out whether or not that imagined world is anything like the real one. Scientific reasoning is, therefore, at all levels an interaction between two episodes of thought - a dialogue between two voices, the one imaginative and the other critical [...]" (Sir Peter B Medawar,  "The Hope of Progress", 1972)

"In moving from conjecture to experimental data, (D), experiments must be designed which make best use of the experimenter's current state of knowledge and which best illuminate his conjecture. In moving from data to modified conjecture, (A), data must be analyzed so as to accurately present information in a manner which is readily understood by the experimenter." (George E P Box & George C Tjao, "Bayesian Inference in Statistical Analysis", 1973)

"Statistical methods are tools of scientific investigation. Scientific investigation is a controlled learning process in which various aspects of a problem are illuminated as the study proceeds. It can be thought of as a major iteration within which secondary iterations occur. The major iteration is that in which a tentative conjecture suggests an experiment, appropriate analysis of the data so generated leads to a modified conjecture, and this in turn leads to a new experiment, and so on." (George E P Box & George C Tjao, "Bayesian Inference in Statistical Analysis", 1973)

"[Great scientists] are men of bold ideas, but highly critical of their own ideas: they try to find whether their ideas are right by trying first to find whether they are not perhaps wrong. They work with bold conjectures and severe attempts at refuting their own conjectures." (Karl R Popper, "The Problem of Demarcation", 1974)

"The essential function of a hypothesis consists in the guidance it affords to new observations and experiments, by which our conjecture is either confirmed or refuted." (Ernst Mach, "Knowledge and Error: Sketches on the Psychology of Enquiry", 1976)

"The verb 'to theorize' is now conjugated as follows: 'I built a model; you formulated a hypothesis; he made a conjecture.'" (John M Ziman, "Reliable Knowledge", 1978)

"All advances of scientific understanding, at every level, begin with a speculative adventure, an imaginative preconception of what might be true - a preconception that always, and necessarily, goes a little way (sometimes a long way) beyond anything which we have logical or factual authority to believe in. It is the invention of a possible world, or of a tiny fraction of that world. The conjecture is then exposed to criticism to find out whether or not that imagined world is anything like the real one. Scientific reasoning is therefore at all levels an interaction between two episodes of thought - a dialogue between two voices, the one imaginative and the other critical; a dialogue, as I have put it, between the possible and the actual, between proposal and disposal, conjecture and criticism, between what might be true and what is in fact the case." (Sir Peter B Medawar, "Pluto’s Republic: Incorporating the Art of the Soluble and Induction Intuition in Scientific Thought", 1982)

"The methods of science include controlled experiments, classification, pattern recognition, analysis, and deduction. In the humanities we apply analogy, metaphor, criticism, and (e)valuation. In design we devise alternatives, form patterns, synthesize, use conjecture, and model solutions." (Béla H Bánáthy, "Designing Social Systems in a Changing World", 1996)

"The everyday usage of 'theory' is for an idea whose outcome is as yet undetermined, a conjecture, or for an idea contrary to evidence. But scientists use the word in exactly the opposite sense. [In science] 'theory' [...] refers only to a collection of hypotheses and predictions that is amenable to experimental test, preferably one that has been successfully tested. It has everything to do with the facts." (Tony Rothman & George Sudarshan, "Doubt and Certainty: The Celebrated Academy: Debates on Science, Mysticism, Reality, in General on the Knowable and Unknowable", 1998)