"If an inquiry thus carefully conducted should fail at last of discovering the truth, it may answer an end perhaps as useful, in discovering to us the weakness of our own understanding. If it does not make us knowing, it may make us modest. If it does not preserve us from error, it may at least from the spirit of error; and may make us cautious of pronouncing with positiveness or with haste, when so much labour may end in so much uncertainty." (Edmund Burke, "Essay on the Sublime and Beautiful", 1756)
"It is the principle of necessity towards which, as to their ultimate centre, all the ideas advanced in this essay immediately converge. In abstract theory the limits of this necessity are determined solely by considerations of man’s proper nature as a human being; but in the application we have to regard, in addition, the individuality of man as he actually exists. This prinsciciple of necessity should, I think, prescribe the grand fundamental rule to which every effort to act on human beings and their manifold relations should be invariably conformed. For it is the only thing which conducts to certain and unquestionable results. The consideration of the useful, which might be opposed to it, does not admit of any true and unswerving decision." (Wilhelm Von Humboldt, "The Limits of State Action", 1792)
"We know the effects of many things, but the causes of few; experience, therefore, is a surer guide than imagination, and inquiry than conjecture." (Charles C Colton, "Lacon", 1820)
"Man's determination not to be deceived is precisely the origin of the problem of knowledge. The question is always and only this: to learn to know and to grasp reality in the midst of a thousand causes of error which tend to vitiate our observation." (Federigo Enriques, "Problems of Science", 1906)
"A system of philosophy, or metaphysics, is a union of a world view and a life view in one harmonious, complete, integral conception. In so far as any man strives to attain, by rational inquiry, a consistent and comprehensive view of life and reality, he is a metaphysician." (Joseph Alexander Leighton, "Man and the Cosmos - An introduction to Metaphysics", 1922)
"Most teachers waste their time by asking questions which are intended to discover what a pupil does not know whereas the true art of questioning has for its purpose to discover what the pupil knows or is capable of knowing." (Albert Einstein, 1920)
"The structure of a theoretical system tells us what alternatives are open in the possible answers to a given question. If observed facts of undoubted accuracy will not fit any of the alternatives it leaves open, the system itself is in need of reconstruction." (Talcott Parsons, "The structure of social action", 1937)
"[The] function of thinking is not just solving an actual problem but discovering, envisaging, going into deeper questions. Often, in great discovery the most important thing is that a certain question is found." (Max Wertheimer, "Productive Thinking", 1945)
"Discovery follows discovery, each both raising and answering questions, each ending a long search, and each providing the new instruments for a new search." (J Robert Oppenheimer, "Prospects in the Arts and Sciences", 1964)
"There are as many types of questions as components in the information." (Jacques Bertin, Semiology of graphics [Semiologie Graphique], 1967)
"[...] bending the question to fit the analysis is to be shunned at all costs." (John W Tukey, "Analyzing Data: Sanctification or Detective Work?", 1969)
"Questions are the engines of intellect, the cerebral machines which convert energy to motion, and curiosity to controlled inquiry." (David H Fischer, "Historians’ Fallacies", 1970)
"Finding the question is often more important than finding the answer." (John W Tukey, "We Need Both Exploratory and Confirmatory", 1980)
"We make our world significant by the courage of our questions and by the depth of our answers." (Carl Sagan, "Cosmos", 1980)
"The purpose of models is not to fit the data but to sharpen the questions." (Samuel Karlin, 1983)
"Each of us carries within us a worldview, a set of assumptions about how the world works - what some call a paradigm - that forms the very questions we allow ourselves to ask, and determines our view of future possibilities." (Frances M Lappé, "Rediscovering America's Values", 1991)
"It is also a good idea to not apply any given technique or method blindly, but to think ahead and see where one could hope such a technique to take one; this can allow one to save enormous amounts of time by eliminating unprofitable directions of inquiry before sinking lots of effort into them, and conversely to give the most promising directions priority."
"[...] we also distinguish knowledge from information, because some pieces of information, such as questions, orders, and absurdities do not constitute knowledge. And also because computers process information but, since they lack minds, they cannot be said to know anything." (Mario Bunge, "Matter and Mind: A Philosophical Inquiry", 2010)
"Meta-analytic thinking is the consideration of any result in relation to previous results on the same or similar questions, and awareness that combination with future results is likely to be valuable. Meta-analytic thinking is the application of estimation thinking to more than a single study. It prompts us to seek meta-analysis of previous related studies at the planning stage of research, then to report our results in a way that makes it easy to include them in future meta-analyses. Meta-analytic thinking is a type of estimation thinking, because it, too, focuses on estimates and uncertainty." (Geoff Cumming, "Understanding the New Statistics", 2012)
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